Title: Cancer stem cells – A brief review

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Topics to be discussed:
Title: Cancer stem cells – A brief review
1. Brief History of Cancer Stem Cells
2. Knowledge gap to be addressed
3. Clinical trials in cancer stem cells
4. Clinical Uses of cancer stem cells
5. Implications in the stem cell therapy in oncology
6. Mechanisms Underlying the Action of Stem Cells in Cancer including
a. A- Homing to Bone Marrow.
b. B- Tumor-Tropic Effect.
c. C. Paracrine Factor Secretion and Differentiation Capacity.
d. D- Signaling in CSCs
7. Stem Cells as Potential Therapeutic Carriers and what is the new target of cancer therapy.
8. Side Effects and Potential Risks of Stem Cell Therapy
9. Advantage and disadvantage of the stem cell therapy in oncology, like: Drug Toxicity
and Drug Resistance, Tumorigenesis, Adverse Events in Allogeneic HSC
Transplantation,).
10. Role of Stem Cells for Immunization Against Tumors
11. Various biomarkers of cancer stem cells in human cancers with the Major signaling
pathways in CSCs
12. Targeting Cell-Surface and Intracellular Markers of Cancer Stem Cells (CSCs) for
Cancer Therapy , I want to be specify on cell surface and intracellular
13. Current and future developments.
Requirements:
 Updated references required (Last 5 years only)
 Minimum 25 references required
 Plagiarism report required
 3500 words required
 Figures and tables wherever necessary

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